![]() ![]() As the amount of inflammation is closely related to scar formation, intense inflammation can induce excessive granulation tissue formation and consequent fibrosis or hypertrophic scar formation. Frequent follow-up was performed every few days or weeks to monitor the healing process and pressure adequacy.Īlthough inflammation is an important event in adult wound healing, a lack of inflammation plays a key role in scar-less wound healing in the early fetus. The endpoint of compression was a little tightness on the inserts and minimal tightness on the normal skin beyond them. The degree of pressure was determined and readjusted according to the wound condition to prevent ischemia, provide a flat surface, and slow the wound contraction with loosening of the surrounding skin. When compression materials were applied, care was taken to avoid the application of excessive pressure, considering the additional pressure induced by their thickness. Various types of elastic bandages, adhesive skin tapes, and compression garments were used as compression materials. After the application of two topical ointments to wounds and adjacent skin regions, thick non-adhesive poly-urethane foam or saline-moistened gauze dressings were applied as inserts to provide definitive pressure and ensure smooth and non-abrasive contact surfaces between wounds and compression materials. ![]() Summary of patents with deep skin defects PatientĬompression therapy was initiated the second week after wounding. ![]()
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